4(1H)-Quinolones with Liver Stage Activity against Plasmodium berghei

With the exception of primaquine, tafenoquine, and atovaquone, there are very few antimalarials that target liver stage parasites. In this study, a transgenic Plasmodium berghei parasite (1052Cl1; PbGFP-Luc(con)) that expresses luciferase was used to assess the anti-liver stage parasite activity of...

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Main Authors: LaCrue, Alexis N., Sáenz, Fabián E., Cross, R. Matthew, Udenze, Kenneth O., Monastyrskyi, Andrii, Stein, Steven, Mutka, Tina S., Manetsch, Roman, Kyle, Dennis E.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2013
Teme:
Susceptibility
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3535941/
https://ncbi.nlm.nih.gov/pubmed/23129047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00793-12
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