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Virus-like glycodendrinanoparticles displaying quasi-equivalent nested polyvalency upon glycoprotein platforms potently block viral infection

Ligand polyvalency is a powerful modulator of protein–receptor interactions. Host–pathogen infection interactions are often mediated by glycan ligand–protein interactions, yet its interrogation with very high copy number ligands has been limited to heterogenous systems. Here we report that through t...

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Dettagli Bibliografici
Autori principali: Ribeiro-Viana, Renato, Sánchez-Navarro, Macarena, Luczkowiak, Joanna, Koeppe, Julia R., Delgado, Rafael, Rojo, Javier, Davis, Benjamin G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Pub. Group 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3535419/
https://ncbi.nlm.nih.gov/pubmed/23250433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms2302
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