Noncoding Sequences Conserved in a Limited Number of Mammals in the SIM2 Interval are Frequently Functional

Cross-species DNA sequence comparison is a fundamental method for identifying biologically important elements, because functional sequences are evolutionarily conserved, wheres nonfunctional sequences drift. A recent genome-wide comparison of human and mouse DNA discovered over 200,000 conserved non...

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Autores principales: Frazer, Kelly A., Tao, Heng, Osoegawa, Kazutoyo, de Jong, Pieter J., Chen, Xiyin, Doherty, Mark F., Cox, David R.
Formato: Artigo
Lenguaje:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2004
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Letters
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC353216/
https://ncbi.nlm.nih.gov/pubmed/14962988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.1961204
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