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Stromal epigenetic dysregulation is sufficient to initiate mouse prostate cancer via paracrine Wnt signaling

Carcinomas most often result from the stepwise acquisition of genetic alterations within the epithelial compartment. The surrounding stroma can also play an important role in cancer initiation and progression. Given the rare frequencies of genetic events identified in cancer-associated stroma, it is...

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Bibliografski detalji
Glavni autori: Zong, Yang, Huang, Jiaoti, Sankarasharma, Devipriya, Morikawa, Teppei, Fukayama, Masashi, Epstein, Jonathan I., Chada, Kiran K., Witte, Owen N.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3528570/
https://ncbi.nlm.nih.gov/pubmed/23184966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1217982109
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