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Methylation of RASSF1A gene promoter is regulated by p53 and DAXX

Inactivation of the tumor suppressor Ras-association domain family 1 isoform A (RASSF1A) due to epigenetic silencing occurs in a variety of human cancers, and still largely unknown are the regulators and mechanisms underlying RASSF1A gene promoter methylation. Herein, we report that this methylation...

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Main Authors: Zhang, Hailong, He, Jing, Li, Jiansha, Tian, Dan, Gu, Lubing, Zhou, Muxiang
Format: Artigo
Jezik:Inglês
Izdano: Federation of American Societies for Experimental Biology 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3528318/
https://ncbi.nlm.nih.gov/pubmed/23038753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.12-215491
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