Short-read reading-frame predictors are not created equal: sequence error causes loss of signal

BACKGROUND: Gene prediction algorithms (or gene callers) are an essential tool for analyzing shotgun nucleic acid sequence data. Gene prediction is a ubiquitous step in sequence analysis pipelines; it reduces the volume of data by identifying the most likely reading frame for a fragment, permitting...

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Bibliographic Details
Main Authors: Trimble, William L, Keegan, Kevin P, D’Souza, Mark, Wilke, Andreas, Wilkening, Jared, Gilbert, Jack, Meyer, Folker
Format: Artigo
Language:Inglês
Published: BioMed Central 2012
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3526449/
https://ncbi.nlm.nih.gov/pubmed/22839106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-13-183
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