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Cell-Extrinsic Effects of Tumor ER Stress Imprint Myeloid Dendritic Cells and Impair CD8(+) T Cell Priming
Tumor-infiltrating myeloid cells, such as dendritic cells (BMDC), are key regulators of tumor growth. However, the tumor-derived signals polarizing BMDC to a phenotype that subverts cell-mediated anti-tumor immunity have yet to be fully elucidated. Addressing this unresolved problem we show that the...
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मुख्य लेखकों: | , , , , , |
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स्वरूप: | Artigo |
भाषा: | Inglês |
प्रकाशित: |
Public Library of Science
2012
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विषय: | |
ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3525659/ https://ncbi.nlm.nih.gov/pubmed/23272178 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0051845 |
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