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How imiquimod licenses plasmacytoid dendritic cells to kill tumors
We have provided evidence for a multifaceted antitumor-function of the Toll-like receptor 7 (TLR7) agonist imiquimod, which rapidly recruits plasmacytoid dendritic cells and possibly other immune cells into tumors by inducing the secretion of CCL2 by dermal cells. Imiquimod induces pDC maturation an...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Landes Bioscience
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3525638/ https://ncbi.nlm.nih.gov/pubmed/23264929 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.22033 |
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