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Expression of plasma cell alloantigen 1 defines layered development of B-1a B-cell subsets with distinct innate-like functions

Innate-like B-1a cells contribute significantly to circulating natural antibodies and mucosal immunity as well as to immunoregulation. Here we show that these classic functions of B-1a cells segregate between two unique subsets defined by expression of plasma cell alloantigen 1 (PC1), also known as...

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Detalhes bibliográficos
Main Authors: Wang, Hongsheng, Shin, Dong-Mi, Abbasi, Sadia, Jain, Shweta, Kovalchuk, Alexander L., Beaty, Natalie, Chen, Sophia, Gonzalez-Garcia, Ines, Morse, Herbert C.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3523855/
https://ncbi.nlm.nih.gov/pubmed/23169635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1212428109
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