Rationale and design of the RIACT–study: a multi-center placebo controlled double blind study to test the efficacy of RItuximab in Acute Cellular tubulointerstitial rejection with B-cell infiltrates in renal Transplant patients: study protocol for a randomized controlled trial

BACKGROUND: Acute kidney allograft rejection is a major cause for declining graft function and has a negative impact on the long-term graft survival. The majority (90%) of acute rejections are T-cell mediated and, therefore, the anti-rejection therapy targets T-cell-mediated mechanisms of the reject...

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書誌詳細
主要な著者: Schiffer, Lena, Schiffer, Mario, Merkel, Saskia, Schwarz, Anke, Mengel, Michael, Jürgens, Christopher, Schroeder, Christoph, Zoerner, Alexander A, Püllmann, Kerstin, Bröcker, Verena, Becker, Jan U, Dämmrich, Maximilian E, Träder, Jana, Großhennig, Anika, Biertz, Frank, Haller, Hermann, Koch, Armin, Gwinner, Wilfried
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2012
主題:
Study Protocol
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3522060/
https://ncbi.nlm.nih.gov/pubmed/23101480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1745-6215-13-199
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