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Linkage disequilibrium analysis reveals an albuminuria risk haplotype containing three missense mutations in the cubilin gene with striking differences among European and African ancestry populations
BACKGROUND: A recent meta-analysis described a variant (p.Ile2984Val) in the cubilin gene (CUBN) that is associated with levels of albuminuria in the general population and in diabetics. METHODS: We implemented a Linkage Disequilibrium (LD) search with data from the 1000 Genomes Project, on African...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2012
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3519576/ https://ncbi.nlm.nih.gov/pubmed/23114252 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2369-13-142 |
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