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Myocilin, a Component of a Membrane-Associated Protein Complex Driven by a Homologous Q-SNARE Domain

Myocilin is a widely expressed protein with no known function, however, mutations in myocilin appear to manifest uniquely as ocular hypertension and the blinding disease glaucoma. Using the protein homology/analogy recognition engine (PHYRE) we find that the olfactomedin domain of myocilin is simila...

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Autori principali: Dismuke, W. Michael, McKay, Brian S., Stamer, W. Daniel
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3518843/
https://ncbi.nlm.nih.gov/pubmed/22463803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi300073r
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