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Myocilin, a Component of a Membrane-Associated Protein Complex Driven by a Homologous Q-SNARE Domain

Myocilin is a widely expressed protein with no known function, however, mutations in myocilin appear to manifest uniquely as ocular hypertension and the blinding disease glaucoma. Using the protein homology/analogy recognition engine (PHYRE) we find that the olfactomedin domain of myocilin is simila...

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Bibliographische Detailangaben
Hauptverfasser: Dismuke, W. Michael, McKay, Brian S., Stamer, W. Daniel
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3518843/
https://ncbi.nlm.nih.gov/pubmed/22463803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi300073r
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