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Understanding Cullin-RING E3 Biology through Proteomics-based Substrate Identification

Protein turnover through the ubiquitin-proteasome pathway controls numerous developmental decisions and biochemical processes in eukaryotes. Central to protein ubiquitylation are ubiquitin ligases, which provide specificity in targeted ubiquitylation. With more than 600 ubiquitin ligases encoded by...

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Detalhes bibliográficos
Main Authors: Harper, J. Wade, Tan, Meng-Kwang Marcus
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3518111/
https://ncbi.nlm.nih.gov/pubmed/22962057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.R112.021154
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