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Understanding Cullin-RING E3 Biology through Proteomics-based Substrate Identification

Protein turnover through the ubiquitin-proteasome pathway controls numerous developmental decisions and biochemical processes in eukaryotes. Central to protein ubiquitylation are ubiquitin ligases, which provide specificity in targeted ubiquitylation. With more than 600 ubiquitin ligases encoded by...

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Hlavní autoři: Harper, J. Wade, Tan, Meng-Kwang Marcus
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Biochemistry and Molecular Biology 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3518111/
https://ncbi.nlm.nih.gov/pubmed/22962057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.R112.021154
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