A novel nutrient sensing mechanism underlies substrate-induced regulation of monocarboxylate transporter-1

Monocarboxylate transporter isoform-1 (MCT1) plays an important role in the absorption of short-chain fatty acids (SCFAs) in the colon. Butyrate, a major SCFA, serves as the primary energy source for the colonic mucosa, maintains epithelial integrity, and ameliorates intestinal inflammation. Previou...

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Bibliographische Detailangaben
Hauptverfasser: Borthakur, Alip, Priyamvada, Shubha, Kumar, Anoop, Natarajan, Arivarasu A., Gill, Ravinder K., Alrefai, Waddah A., Dudeja, Pradeep K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2012
Schlagworte:
Mucosal Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3517653/
https://ncbi.nlm.nih.gov/pubmed/22982338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00308.2012
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