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A spatially-organized multicellular innate immune response in lymph nodes limits systemic pathogen spread

The lymphatic network that transports interstitial fluid and antigens to lymph nodes constitutes a conduit system that can be hijacked by invading pathogens to achieve systemic spread unless dissemination is blocked in the lymph node itself. Here we show that a network of diverse lymphoid cells (NK...

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Autori principali: Kastenmüller, Wolfgang, Torabi-Parizi, Parizad, Subramanian, Naeha, Lämmermann, Tim, Germain, Ronald N.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3514884/
https://ncbi.nlm.nih.gov/pubmed/22980983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.07.021
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