IκBα and IκBβ possess injury context-specific functions that uniquely influence hepatic NF-κB induction and inflammation

IκB proteins play an important role in regulating NF-κB induction following a diverse range of environmental injuries. Studies evaluating IκBβ knock-in mice (AKBI), in which the IκBα gene is replaced by the IκBβ cDNA, have uncovered divergent properties of IκBα and IκBβ that influence their ability...

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Detalhes bibliográficos
Main Authors: Fan, Chenguang, Li, Qiang, Zhang, Yulong, Liu, Xiaoming, Luo, Meihui, Abbott, Duane, Zhou, Weihong, Engelhardt, John F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2004
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC351311/
https://ncbi.nlm.nih.gov/pubmed/14991073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200417337
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