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IκBα and IκBβ possess injury context-specific functions that uniquely influence hepatic NF-κB induction and inflammation
IκB proteins play an important role in regulating NF-κB induction following a diverse range of environmental injuries. Studies evaluating IκBβ knock-in mice (AKBI), in which the IκBα gene is replaced by the IκBβ cDNA, have uncovered divergent properties of IκBα and IκBβ that influence their ability...
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| Autors principals: | , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Clinical Investigation
2004
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC351311/ https://ncbi.nlm.nih.gov/pubmed/14991073 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200417337 |
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