Concomitant BDNF and sleep slow wave changes indicate ketamine-induced plasticity in major depressive disorder

The N-methyl-d-aspartate (NMDA) receptor antagonist ketamine has rapid antidepressant effects in treatment-resistant major depressive disorder (MDD). In rats, ketamine selectively increased electro-encephalogram (EEG) slow wave activity (SWA) during non-rapid eye movement (REM) sleep and altered cen...

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Hauptverfasser: Duncan, Wallace C., Sarasso, Simone, Ferrarelli, Fabio, Selter, Jessica, Riedner, Brady A., Hejazi, Nadia S., Yuan, Peixiong, Brutsche, Nancy, Manji, Husseini K., Tononi, Giulio, Zarate, Carlos A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3510337/
https://ncbi.nlm.nih.gov/pubmed/22676966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1017/S1461145712000545
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