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Molecular Modeling Study on Tunnel Behavior in Different Histone Deacetylase Isoforms
Histone deacetylases (HDACs) have emerged as effective therapeutic targets in the treatment of various diseases including cancers as these enzymes directly involved in the epigenetic regulation of genes. However the development of isoform-selective HDAC inhibitors has been a challenge till date sinc...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3510210/ https://ncbi.nlm.nih.gov/pubmed/23209570 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0049327 |
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