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Mutations Associated with Functional Disorder of Xanthine Oxidoreductase and Hereditary Xanthinuria in Humans

Xanthine oxidoreductase (XOR) catalyzes the conversion of hypoxanthine to xanthine and xanthine to uric acid with concomitant reduction of either NAD(+) or O(2). The enzyme is a target of drugs to treat hyperuricemia, gout and reactive oxygen-related diseases. Human diseases associated with genetica...

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Detalles Bibliográficos
Main Authors: Ichida, Kimiyoshi, Amaya, Yoshihiro, Okamoto, Ken, Nishino, Takeshi
Formato: Artigo
Idioma:Inglês
Publicado: Molecular Diversity Preservation International (MDPI) 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3509653/
https://ncbi.nlm.nih.gov/pubmed/23203137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms131115475
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