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Mutations Associated with Functional Disorder of Xanthine Oxidoreductase and Hereditary Xanthinuria in Humans

Xanthine oxidoreductase (XOR) catalyzes the conversion of hypoxanthine to xanthine and xanthine to uric acid with concomitant reduction of either NAD(+) or O(2). The enzyme is a target of drugs to treat hyperuricemia, gout and reactive oxygen-related diseases. Human diseases associated with genetica...

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Détails bibliographiques
Auteurs principaux: Ichida, Kimiyoshi, Amaya, Yoshihiro, Okamoto, Ken, Nishino, Takeshi
Format: Artigo
Langue:Inglês
Publié: Molecular Diversity Preservation International (MDPI) 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3509653/
https://ncbi.nlm.nih.gov/pubmed/23203137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms131115475
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