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Obesity and IL-6 interact in modulating the response to endotoxemia in mice

Obesity is associated with elevated levels of IL-6. High IL-6 is prognostic of mortality in sepsis, while controversial data link obesity to sepsis outcome. We used Lean and Diet-Induced Obese (DIO) WT and IL-6 KO mice to investigate the interaction between obesity and IL-6 in endotoxemia. Circulati...

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Hlavní autoři: Pini, Maria, Castellanos, Karla J., Rhodes, Davina H., Fantuzzi, Giamila
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3505261/
https://ncbi.nlm.nih.gov/pubmed/23010503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cyto.2012.08.027
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