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The Mechanisms of Cerebral Vascular Dysfunction and Neuroinflammation by MMP-mediated Degradation of VEGFR-2 in Alcohol Ingestion
OBJECTIVE: Blood-brain barrier (BBB) dysfunction caused by activation of matrix metalloproteinases (MMPs) is a pathological feature in vascular/neurological disease. Here, we describe the mechanisms of BBB dysfunction and neuroinflammation as a result of MMP-3/9 activation and disruption of VEGF-A/V...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3501346/ https://ncbi.nlm.nih.gov/pubmed/22402362 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.112.247668 |
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