The Capping Domain in RalF Regulates Effector Functions

The Legionella pneumophila effector protein RalF functions as a guanine nucleotide exchange factor (GEF) that activates the host small GTPase protein ADP-ribosylation factor (Arf), and recruits this host protein to the vacuoles in which this pathogen resides. GEF activity is conferred by the Sec7 do...

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Autors principals: Alix, Eric, Chesnel, Laurent, Bowzard, Brad J., Tucker, Aimee M., Delprato, Anna, Cherfils, Jacqueline, Wood, David O., Kahn, Richard A., Roy, Craig R.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3499574/
https://ncbi.nlm.nih.gov/pubmed/23166491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003012
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