Molecular mechanism of cytotoxicity induced by Hsp90-targeted Antp-TPR hybrid peptide in glioblastoma cells

BACKGROUND: Heat-shock protein 90 (Hsp90) is vital to cell survival under conditions of stress, and binds client proteins to assist in protein stabilization, translocation of polypeptides across cell membranes, and recovery of proteins from aggregates. Therefore, Hsp90 has emerged as an important ta...

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Detaylı Bibliyografya
Asıl Yazarlar: Horibe, Tomohisa, Torisawa, Aya, Kohno, Masayuki, Kawakami, Koji
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2012
Konular:
Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3499401/
https://ncbi.nlm.nih.gov/pubmed/22913813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-11-59
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