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Plasticity of the asialoglycoprotein receptor deciphered by ensemble FRET imaging and single-molecule counting PALM imaging

The stoichiometry and composition of membrane protein receptors are critical to their function. However, the inability to assess receptor subunit stoichiometry in situ has hampered efforts to relate receptor structures to functional states. Here, we address this problem for the asialoglycoprotein re...

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Autori principali: Renz, Malte, Daniels, Brian R., Vámosi, György, Arias, Irwin M., Lippincott-Schwartz, Jennifer
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3497821/
https://ncbi.nlm.nih.gov/pubmed/23043115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1211753109
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