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Immunomodulatory glycan LNFPIII alleviates hepatosteatosis and insulin resistance through direct and indirect control of metabolic pathways

Parasitic worms express host-like glycans to attenuate the immune response of human hosts. The therapeutic potential of this immunomodulatory mechanism in controlling metabolic dysfunction associated with chronic inflammation remains unexplored. We demonstrate here that administration of Lacto-N-fuc...

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Detalhes bibliográficos
Main Authors: Bhargava, Prerna, Li, Changlin, Stanya, Kristopher J., Jacobi, David, Dai, Lingling, Liu, Sihao, Gangl, Matthew R., Harn, Donald A., Lee, Chih-Hao
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3493877/
https://ncbi.nlm.nih.gov/pubmed/23104131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.2962
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