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A Graphical Modelling Approach to the Dissection of Highly Correlated Transcription Factor Binding Site Profiles
Inferring the combinatorial regulatory code of transcription factors (TFs) from genome-wide TF binding profiles is challenging. A major reason is that TF binding profiles significantly overlap and are therefore highly correlated. Clustered occurrence of multiple TFs at genomic sites may arise from c...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3493460/ https://ncbi.nlm.nih.gov/pubmed/23144600 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002725 |
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