In Vitro–Reduced Susceptibility to Artemether in P. falciparum and Its Association With Polymorphisms on Transporter Genes

Plasmodium falciparum with reduced sensitivity to artemisinin derivatives has been observed in endemic areas, but the molecular mechanisms for this reduced sensitivity remain unclear. We evaluated the association between in vitro susceptibility of P. falciparum isolates obtained from southwest Niger...

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Autori principali: Bustamante, Carolina, Folarin, Onikepe A., Gbotosho, Grace O., Batista, Camila N., Mesquita, Elieth A., Brindeiro, Rodrigo M., Tanuri, Amilcar, Struchiner, Claudio J., Sowunmi, Akintunde, Oduola, Ayoade, Wirth, Dyann F., Zalis, Mariano G., Happi, Christian T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2012
Soggetti:
Major Articles and Brief Reports
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3490696/
https://ncbi.nlm.nih.gov/pubmed/22615315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jis359
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