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Inhibition of laminin-8 in vivo using a novel poly(malic acid)-based carrier reduces glioma angiogenesis

We have previously shown that laminin-8, a vascular basement membrane component, was over-expressed in human glioblastomas multiforme and their adjacent tissues compared to normal brain. Increased laminin-8 correlated with shorter glioblastoma recurrence time and poor patient survival making it a po...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Fujita, Manabu, Khazenzon, Natalya M., Ljubimov, Alexander V., Lee, Bong-Seop, Virtanen, Ismo, Holler, Eggehard, Black, Keith L., Ljubimova, Julia Y.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2006
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3487708/
https://ncbi.nlm.nih.gov/pubmed/17109197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10456-006-9046-9
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