Targeting intratumoral B cells with rituximab in addition to CHOP in angioimmunoblastic T-cell lymphoma. A clinicobiological study of the GELA

BACKGROUND: In angioimmunoblastic T-cell lymphoma, symptoms linked to B-lymphocyte activation are common, and variable numbers of CD20(+) large B-blasts, often infected by Epstein-Barr virus, are found in tumor tissues. We postulated that the disruption of putative B-T interactions and/or depletion...

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Autori principali: Delfau-Larue, Marie-Hélène, de Leval, Laurence, Joly, Bertrand, Plonquet, Anne, Challine, Dominique, Parrens, Marie, Delmer, Alain, Salles, Gilles, Morschhauser, Franck, Delarue, Richard, Brice, Pauline, Bouabdallah, Reda, Casasnovas, Olivier, Tilly, Hervé, Gaulard, Philippe, Haioun, Corinne
Natura: Artigo
Lingua:Inglês
Pubblicazione: Ferrata Storti Foundation 2012
Soggetti:
Original Articles and Brief Reports
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3487562/
https://ncbi.nlm.nih.gov/pubmed/22371178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2011.061507
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