In Vivo and In Vitro Suppression of Hepatocellular Carcinoma by EF24, a Curcumin Analog

The synthetic compound 3,5-bis(2-flurobenzylidene)piperidin-4-one (EF24) is a potent analog of curcumin that exhibits enhanced biological activity and bioavailability without increasing toxicity. EF24 exerts antitumor activity by arresting the cell cycle and inducing apoptosis, suppressing many type...

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Bibliographic Details
Main Authors: Liu, Haitao, Liang, Yingjian, Wang, Luoluo, Tian, Lantian, Song, Ruipeng, Han, Tianwen, Pan, Shangha, Liu, Lianxin
Format: Artigo
Language:Inglês
Published: Public Library of Science 2012
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3485291/
https://ncbi.nlm.nih.gov/pubmed/23118928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0048075
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