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Galectin-9 Ameliorates Con A-Induced Hepatitis by Inducing CD4(+)CD25(low/int) Effector T-Cell Apoptosis and Increasing Regulatory T Cell Number

BACKGROUND: T cell-mediated liver damage is a key event in the pathogenesis of many chronic human liver diseases, such as liver transplant rejection, primary biliary cirrhosis, and sclerosing cholangitis. We and other groups have previously reported that galectin-9, one of the β-galactoside binding...

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Hlavní autoři: Lv, Kun, Zhang, Yingying, Zhang, Mengying, Zhong, Min, Suo, Qifeng
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3485226/
https://ncbi.nlm.nih.gov/pubmed/23118999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0048379
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