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MC1R variants predisposing to concomitant primary cutaneous melanoma in a monozygotic twin pair
BACKGROUND: Concomitant primary cutaneous melanoma in monozygotic twins has been reported in only two pairs but in neither of them genetic analysis was performed. Two high-penetrance susceptibility genes, CDKN2A and CDK4 and one low-penetrance gene, MC1R, are well-defined genetic risk factors for me...
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| Main Authors: | , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
BioMed Central
2012
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3483249/ https://ncbi.nlm.nih.gov/pubmed/22978401 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-13-81 |
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