Sustained Submicromolar H(2)O(2) Levels Induce Hepcidin via Signal Transducer and Activator of Transcription 3 (STAT3)

The peptide hormone hepcidin regulates mammalian iron homeostasis by blocking ferroportin-mediated iron export from macrophages and the duodenum. During inflammation, hepcidin is strongly induced by interleukin 6, eventually leading to the anemia of chronic disease. Here we show that hepatoma cells...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Millonig, Gunda, Ganzleben, Ingo, Peccerella, Teresa, Casanovas, Guillem, Brodziak-Jarosz, Lidia, Breitkopf-Heinlein, Katja, Dick, Tobias P., Seitz, Helmut-Karl, Muckenthaler, Martina U., Mueller, Sebastian
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2012
Témata:
Molecular Bases of Disease
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3481342/
https://ncbi.nlm.nih.gov/pubmed/22932892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.358911
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky