Glycodelin-A Stimulates Interleukin-6 Secretion by Human Monocytes and Macrophages through L-selectin and the Extracellular Signal-regulated Kinase Pathway

Macrophages represent the second major type of decidual leukocytes at the fetomaternal interface. Changes in macrophage number and activity are associated with fetal loss and pregnancy complications. Glycodelin-A (GdA) is an abundant glycoprotein in the first-trimester decidua. It is involved in fet...

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Main Authors: Lee, Cheuk-Lun, Lam, Eve Y. F., Lam, Kevin K. W., Koistinen, Hannu, Seppälä, Markku, Ng, Ernest H. Y., Yeung, William S. B., Chiu, Philip C. N.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2012
Fag:
Cell Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3481301/
https://ncbi.nlm.nih.gov/pubmed/22977256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.385336
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