Antihyperalgesic activity of nucleoside transport inhibitors in models of inflammatory pain in guinea pigs

BACKGROUND AND METHODS: The role of the endogenous purine nucleoside, adenosine, in nociception is well established. Inhibition of the equilibrative nucleoside transporter (ENT1) prevents adenosine uptake into cells, and could therefore enhance the antinociceptive properties of adenosine. The effect...

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Bibliographic Details
Main Authors: Maes, Sabine S, Pype, Stefan, Hoffmann, Vincent LH, Biermans, Maria, Meert, Theo F
Format: Artigo
Language:Inglês
Published: Dove Medical Press 2012
Subjects:
Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3474157/
https://ncbi.nlm.nih.gov/pubmed/23091396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/JPR.S35108
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