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Antihyperalgesic activity of nucleoside transport inhibitors in models of inflammatory pain in guinea pigs

BACKGROUND AND METHODS: The role of the endogenous purine nucleoside, adenosine, in nociception is well established. Inhibition of the equilibrative nucleoside transporter (ENT1) prevents adenosine uptake into cells, and could therefore enhance the antinociceptive properties of adenosine. The effect...

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Библиографические подробности
Главные авторы: Maes, Sabine S, Pype, Stefan, Hoffmann, Vincent LH, Biermans, Maria, Meert, Theo F
Формат: Artigo
Язык:Inglês
Опубликовано: Dove Medical Press 2012
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3474157/
https://ncbi.nlm.nih.gov/pubmed/23091396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/JPR.S35108
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