Silencing of MicroRNA-21 Confers Radio-Sensitivity through Inhibition of the PI3K/AKT Pathway and Enhancing Autophagy in Malignant Glioma Cell Lines

Radiation is a core part of therapy for malignant glioma and is often provided following debulking surgery. However, resistance to radiation occurs in most patients, and the underlying molecular mechanisms of radio-resistance are not fully understood. Here, we demonstrated that microRNA 21 (miR-21),...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Gwak, Ho-Shin, Kim, Tae Hoon, Jo, Guk Heui, Kim, Youn-Jae, Kwak, Hee-Jin, Kim, Jong Heon, Yin, Jinlong, Yoo, Heon, Lee, Seung Hoon, Park, Jong Bae
التنسيق: Artigo
اللغة:Inglês
منشور في: Public Library of Science 2012
الموضوعات:
Research Article
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC3471817/
https://ncbi.nlm.nih.gov/pubmed/23077620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0047449
الوسوم: إضافة وسم
لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!

مواد مشابهة