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The Pseudomonas aeruginosa N-Acylhomoserine Lactone Quorum Sensing Molecules Target IQGAP1 and Modulate Epithelial Cell Migration

Quorum sensing (QS) signaling allows bacteria to control gene expression once a critical population density is achieved. The Gram-negative human pathogen Pseudomonas aeruginosa uses N-acylhomoserine lactones (AHL) as QS signals, which coordinate the production of virulence factors and biofilms. Thes...

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Bibliographic Details
Main Authors: Karlsson, Thommie, Turkina, Maria V., Yakymenko, Olena, Magnusson, Karl-Eric, Vikström, Elena
Format: Artigo
Language:Inglês
Published: Public Library of Science 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3469656/
https://ncbi.nlm.nih.gov/pubmed/23071436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002953
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