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Intratumoral Immunotherapy of Established Solid Tumors with Chitosan/IL-12
IL-12 is a potent antitumor cytokine that exhibits significant clinical toxicities following systemic administration. We hypothesized that intratumoral (i.t.) administration of IL-12 coformulated with the biodegradable polysaccharide chitosan could enhance the antitumor activity of IL-12 while limit...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2010
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3468951/ https://ncbi.nlm.nih.gov/pubmed/20664357 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CJI.0b013e3181eb826d |
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