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Characterization of EPPIN's Semenogelin I Binding Site: A Contraceptive Drug Target

Epididymal protease inhibitor (EPPIN) is found on the surface of spermatozoa and works as a central hub for a sperm surface protein complex (EPPIN protein complex [EPC]) that inhibits sperm motility on the binding of semenogelin I (SEMG1) during ejaculation. Here, we identify EPPIN's amino acid...

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Autors principals: Silva, Erick J.R., Hamil, Katherine G., Richardson, Richard T., O'Rand, Michael G.
Format: Artigo
Idioma:Inglês
Publicat: Society for the Study of Reproduction, Inc. 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3463412/
https://ncbi.nlm.nih.gov/pubmed/22699487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.112.101832
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