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Dysfunction of the prefrontal cortex in addiction: neuroimaging findings and clinical implications

The loss of control over drug intake that occurs in addiction was initially believed to result from disruption of subcortical reward circuits. However, imaging studies in addictive behaviours have identified a key involvement of the prefrontal cortex (PFC) both through its regulation of limbic rewar...

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Bibliographic Details
Main Authors: Goldstein, Rita Z., Volkow, Nora D.
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3462342/
https://ncbi.nlm.nih.gov/pubmed/22011681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrn3119
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