An Early Reduction in Treg Cells Correlates with Enhanced Local Inflammation in Cutaneous Leishmaniasis in CCR6-Deficient Mice

Resistance to Leishmania major infection is dependent on the development of a cell-mediated Th1 immune response in resistant C57BL/6 mice whereas Th2-prone BALB/c mice develop non-healing lesions after infection. The chemokine receptor CCR6 is shared by anti-inflammatory regulatory T cells and pro-i...

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Main Authors: Barth, Thomas, Schmidt, Dominic, Botteron, Catherine, Nguyen, Trang T. T., Ritter, Uwe, Männel, Daniela N., Lechner, Anja
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2012
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3460949/
https://ncbi.nlm.nih.gov/pubmed/23028548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0044499
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