IRF5 SLE-Risk Haplotype is Associated with Asymptomatic Serologic Autoimmunity and Progression to Clinical Autoimmunity in Neonatal Lupus Mothers

OBJECTIVE: Genetic variation in interferon regulatory factor 5 (IRF5) has been associated with risk of developing systemic lupus erythematosus (SLE), and this association is largely dependent upon anti-Ro autoantibodies. We studied a unique cohort of anti-Ro positive individuals with diverse diagnos...

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Detalhes bibliográficos
Main Authors: Cherian, Tharian S., Kariuki, Silvia N., Franek, Beverly S., Buyon, Jill P., Clancy, Robert M., Niewold, Timothy B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3449035/
https://ncbi.nlm.nih.gov/pubmed/22674082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.34571
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