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Attenuated Mycobacterium tuberculosis SO2 Vaccine Candidate Is Unable to Induce Cell Death

It has been proposed that Mycobacterium tuberculosis virulent strains inhibit apoptosis and trigger cell death by necrosis of host macrophages to evade innate immunity, while non-virulent strains induce typical apoptosis activating a protective host response. As part of the characterization of a nov...

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Detalhes bibliográficos
Main Authors: Aporta, Adriana, Arbues, Ainhoa, Aguilo, Juan I., Monzon, Marta, Badiola, Juan J., de Martino, Alba, Ferrer, Nadia, Marinova, Dessislava, Anel, Alberto, Martin, Carlos, Pardo, Julian
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3446966/
https://ncbi.nlm.nih.gov/pubmed/23028853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0045213
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