Hypoxia Enhances the Proliferative Response of Macrophages to CSF-1 and Their Pro-Survival Response to TNF

In chronic inflammatory lesions there are increased numbers of macrophages with a possible contribution of enhanced survival/proliferation due, for example, to cytokine action; such lesions are often hypoxic. Prior studies have found that culture in low oxygen can promote monocyte/macrophage surviva...

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Bibliographic Details
Main Authors: Hamilton, John A., Lacey, Derek C., Turner, Amanda, de Kok, Bernard, Huynh, Jennifer, Scholz, Glen M.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2012
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3446916/
https://ncbi.nlm.nih.gov/pubmed/23029275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0045853
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