Bone marrow-derived, alternatively activated macrophages enhance solid tumor growth and lung metastasis of mammary carcinoma cells in a Balb/C mouse orthotopic model

INTRODUCTION: Tumor-associated macrophages, which are derived from the infiltration of circulating bone marrow-derived monocytes, consist primarily of a polarized M2 macrophage (M2-Mϕ) population and are associated with poor prognosis in various cancers. In the present study, we attempted to assess...

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Bibliographic Details
Main Authors: Cho, Han Jin, Jung, Jae In, Lim, Do Young, Kwon, Gyoo Taik, Her, Song, Park, Jong Hoon, Park, Jung Han Yoon
Format: Artigo
Language:Inglês
Published: BioMed Central 2012
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3446344/
https://ncbi.nlm.nih.gov/pubmed/22616919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr3195
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